apalutamide will minimize the extent or impact of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration of apalutamide, a strong CYP3A4 inducer, with medication which might be CYP3A4 substrates may end up in lessen publicity to those remedies.Doses may very well be amplified little by littl